• The recommended dose of Duaklir® Genuair® is one inhalation of 400/12mcg twice a day, once in the morning and once in the evening.  It is indicated for use in adults only.

• Duaklir® Genuair® contains two active ingredients, aclidinium bromide and formoterol fumarate dihydrate.
  • Aclidinium bromide is a long-acting muscarinic antagonist (LAMA)
  • Formoterol fumarate dihydrate is a long-acting beta2-agonist (LABA)
• Both belong to a group of medicines called bronchodilators. Bronchodilators help to open and relax the muscles of the airways. This allows more air to get in and out of the lungs. This makes it easier for patients with COPD to breathe and helps prevent shortness of breath and wheezing.

• Like all medicines, Duaklir® Genuair® can cause side effects, although not everybody gets them.
• Side effects may include:
  • inflammation or irritiation of the nose and throat
  • headache
  • urinary tract infection
  • throat pain
  • dizziness
  • muscle pain, cramps, spasms
  • flu
  • difficulty sleeping (insomnia)
  • tooth infection
  • chest pain
  • shaking/tremor
  • cough
  • diarrhea, nausea
  • dry mouth
  • anxiety, agititation
  • rash, skin itching
  • distorted sense of taste
  • blurred vision
  • increased blood pressure
  • swelling of the hands or feet
• If any of these affects you severely, tell your doctor or pharmacist.

• Before you use Duaklir® Genuair® talk to your doctor or pharmacist if you:
  • have heart problems, such as rapid or irregular heart beat or an abnormal electrical signal called "prolongation fo the QT interval"
  • have high blood pressure
  • have diabetes
  • have low levels of potassium in your blood
  • have seizures
  • have thyroid gland problems or disease
  • have a tumor in one of your adrenal glands (phaeochromocytoma)
  • are taking similar medicines for your lung disease
  • are taking any medications including eye drops, this includes medications you can buy without prescription
  • have eye problems such as glaucoma, eye pain, blurred vision, see halos around lights or colored images
  • have an enlarged prostate, problems passing urine or painful urination
  • have severe allergy to milk proteins
• Duaklir® Genuair® should not be used more frequently than twice daily. Do not exceed the prescribed dose.
• This medication has been prescribed for you and should not be given to other people.
• Remember to tell any other doctor, dentis, or pharmacist you consult that you are taking this medication.

Drug Interactions: Tell your doctor or pharmacist if you are taking:

• Any medicines that may be similar to Duaklir Genuair to treat breathing difficulties.
• Medicines that lower the amount of potassium in your blood. These include:
  •  corticosteroids that you take by mouth (such as prednisolone),
  •  diuretics(suchasfurosemideorhydrochlorothiazide),
  •  certainmedicinesusedtotreatbreathingconditions(suchastheophylline).
•  Medicines called beta blockers that may be used to treat high blood pressure or other heart problems (such as atenolol or propranolol) or to treat glaucoma (such as timolol).
•  Medicines which can cause a type of change in the electrical activity of the heart known as QT interval prolongation (observed in an electrocardiogram). These include medicines for the treatment of:
  •  depression(suchasmonoamineoxidaseinhibitorsortricyclicantidepressants),
  •  bacterial infections (such as erythromycin, clarithromycin)

Use in pregnancy and lactation:  Human data is limited.  Consult your doctor or pharmacist before use.