The dose of vinorelbine will be different for different people. The dose is individualized based on what it is being used for, body size, and other medications being used.

Vinorelbine is a cancer-fighting medication known as an antineoplastic. It slows or stops the growth of cancer cells by interfering with their DNA, which is necessary for their growth and reproduction.

More common side effects requiring medical attention only if bothersome:

• loss of appetite
• constipation or diarrhea
• jaw pain
• joint or muscle pain
• nausea and vomiting
• temporary loss of hair

Less common side effects that require medical attention:

• loss of strength or energy
• numbness or tingling in the fingers and toes
• unusual tiredness or weakness

Side effects that may indicate a serious side effect. Medical attention is immediately ineeded:

• black, tarry stools or blood in urine or stools
• chest pain
• cough, hoarseness, shortness of breath, sore throat, lower back or side pain or painful urination with fever or chills
• fever or chills
• redness, pain, or discolouration of vein at site of injection
• shortness of breath
• sores in the mouth and on the lips
• unusual bleeding or bruising

Do not take vinorelbine if:

• you are allergic to vinorelbine or are allergic to any component in this medication
• you have severe reductions in the number of circulating platelets and/or white blood cells that was caused by a medication

Talk to your doctor or pharmacist before using vinorelbine if:

• you have had prior radiation or chemotherapy
• you have liver problems
• you have pre-existing neuropathy (nerve problems)

Drug interactions - Consult with your physician or pharmacist if you are taking:

• mitomycin
• cisplatin
• paclitaxel

Use in pregnancy:This medication may cause birth defects if either the father or mother is using vinorelbine at the time of conception, or if it is taken during pregnancy. It may also harm the baby in other ways if taken during pregnancy.

Use in breastfeeding: Because of the potential for severe toxicity, use when breastfeeding is not recommended.